澳洲可以逆转2型糖尿病和放逐胰岛素刺戳的新治疗方法 - 研究人员致敬“令人兴奋”的发现

在澳大利亚中文新闻




A blast of steam is being tested as a treatment for type 2 diabetes that could potentially banish the need for insulin jabs.

The therapy involves hot vapour being fired at the lining of the duodenum – the first part of the small intestine – to deliberately damage it.

Research shows that people with type 2 diabetes whose diet is high in carbohydrates, fats and sugar often have a much thicker duodenum lining (or mucosa).

Scientists believe that high levels of blood sugar and the subsequent release of the hormone insulin causes signals in the body to promote cell and tissue growth.这会导致衬里变得充满活力,对胰岛素不敏感 - 导致2型糖尿病。

,但是在新治疗中,一旦新治疗的表面的最高表面已经“再生”,它可以使患者的胰岛素更加敏感,而摩尔(Forma)又可以恢复到正常水平。 a clinical trial in centres across Europe and Brazil, published in the journal Diabetes Research and Clinical Practice in 2022, found that after two years, patients’ blood sugar levels were ‘significantly reduced’ and more than 50 per cent of them reduced their diabetes medications, or kept them constant (rather than having to increase the dose).

In a small tr​​ial involving a newer form of the treatment, given对于智利的20名患者来说,发现在治疗后九个月,所有人都能够停止其胰岛素刺痛(尽管有些仍在口服药物中),正如GIE最近报道的,《美国胃肠道内窥镜学杂志》。 src =“ https://i.dailymail.co.uk/1s/2025/09/09/19/101951277-15078069-Image-image-image-image-a-9_1757355557746.jpg”通过蒸汽伤害“重新生成”,它可能再次变得对胰岛素更加敏感,患者的血糖水平恢复正常“ class =” class =“ blkborder img-share” style =“ max-width:100%“加载” />

又可以在新治疗后再次造成的损害。患者的血糖水平恢复正常

大约有四分之一的英国有580万人中有四分之一被诊断出患有2型糖尿病的人依靠胰岛素注射来管理他们的状况 weight-loss surgery (where the stomach is made smaller) can also dramatically improve blood-sugar control.

‘What we’ve noticed over the past few decades is that when people underwent gastric bypass surgery to help them lose weight, it can also hugely improve their type 2 diabetes,’ explains Arin Saha, a consultant in general, upper gastrointestinal and bariatric surgery在Calderdale和Huddersfield NHS Trust。归因于体重减轻。

’因此,研究人员开始研究另一种解释。我们发现,养分仅在小肠中才吸收,这意味着葡萄糖水平更为正常。’

,人们认为这些十二指肠在“信号”中起着重要作用,在对身体的“信号传导”中起着重要的作用,这些营养成分来自胃而需要吸收的营养。十二指肠可能意味着这个过程不再有效地发生。

“

tever原因是十二指肠功能障碍发生在2型糖尿病患者中。’

’‘当您考虑糖尿病时,您通常会想到肝脏产生葡萄糖和胰腺产生胰岛素。但是现在还有另一个器官,即十二指肠,我们认为这在导致糖尿病的人产生更多的葡萄糖和不足以应对的胰岛素。'

基于对DuododeNum的理解,研究人员开始寻求与GASTRIC相同的好处,从而获得了不太极端的方式,从而获得了与GASTRIC相同的好处。首先,他们使用一种称为十二指肠粘膜消融的程序“重新铺面”十二指肠。

在此15厘米长的十二指肠衬里的15厘米长的一部分被用类似热液的液体沿着流动的液体播放的热液,沿着classe classage

plastage。使用称为射频蒸气消融的技术的方法,该技术沿着内窥镜传递导管装置(一种带有微型相机的柔性管,还可以插入外科手术工具),从而释放出每持续的蒸汽的爆炸爆炸。狮子的鬃毛给我带来了可怕的副作用。不要弄错我的错误

该过程大约需要半小时,并使用加热到90c的液体。 class="mol-para-with-font">While the full results of the study should be published next year, ‘patients have gone from an average HbA1c [a way of measuring average blood sugar levels over two to three months] of around 9.3 per cent to 7.6 per cent [an ideal reading is under 6.5 per cent].’

Currently the treatment is not available in the UK.

A review published last year by the National Institute for Health and Care Excellence looking at existing studies into duodenal mucosa resurfacing, recommended that for now it should only be done as part of a formal research study.

Dr Haidry is now seeking approval for a UK trial, which he hopes will happen next year.

对这种方法发表评论,萨哈先生对身体健康说:‘这种新的可能解决糖尿病的新方法令人兴奋,因此更多的研究结果将非常有趣。

’这可能是一种可以解决越来越多的人与2型糖尿病的人相处的工具。
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