A new test taken two weeks after starting treatment for breast cancer can tell if the disease is likely to return.
The breakthrough could spare thousands of patients unnecessary therapy while allowing others to receive more intensive care sooner.
Researchers at The Institute of Cancer Research, London, found taking两周的激素药物改变了某些肿瘤的特征，导致它们转移亚型。
具有最高风险的复发风险的患者具有一种称为腔内B的肿瘤类型，该肿瘤在此短期治疗后没有变化。 intensive treatment that others could avoid.
Experts say the findings, published in the journal eBioMedicine, highlight the benefit of taking hormone therapy before surgery to help guide doctors’ decision making.
The new test works for a type of breast cancer known as oestrogen receptor positive, human epidermal growth factor receptor 2积极的是，全球大约有200,000例。 src =“ https://i.dailymail.co.uk/1s/2025/07/18/17/995427777-1491919315-Image-image-image-image-a-1_175285447290.jpg” style="max-width:100%" loading="lazy" />
‘While current classification relies on hormone receptor and HER2 status, we know that patients within these groups can respond very differently to the same therapy.
‘Our earlier research identified distinct molecular subtypes within HER2-positive, oestrogen receptor-positive breast cancer.
‘In this new study, we’ve shown that these subtypes can shift after just two weeks of hormone therapy.
‘This insight helps us identify which patients are likely to respond well and which may show early signs of treatment resistance, offering the opportunity更快地量身定制治疗策略。 ’
慈善乳腺癌首席科学官西蒙·文森特（Simon Vincent）博士，该研究部分资助了这项研究：'这些发现增加了越来越多的证据，表明基因组检测可以在预测女性乳腺癌的风险中起着强大的作用，尤其是在Er-Posistic concer ’‘未来女性有可能从这项研究中受益匪浅，它确保了她们避免接受不必要的治疗并导致更具个性化的治疗计划，以便妇女获得针对其特定类型乳腺癌的最有效治疗。’
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